Bruderholz is home to 9,610 people and covers 2.6 square kilometers, making it the fourth-largest neighborhood in Basel. It lies on a prominent hill in the southern part of the city, bordered by Gundeldingen, St. Alban, and the suburban communities of Münchenstein, Reinach, Binningen, and Bottmingen.

The most remarkable feature of Bruderholz is its exceptionally high share of single-family homes. At 72.1 percent, this is by far the highest proportion in all of Basel, far above any other neighborhood. This figure alone defines the character of the area as a spacious, suburban-style enclave within the city.

Bruderholz is one of the larger neighborhoods in Basel, covering 7.2 percent of the canton's surface. Its population is notably Swiss, with foreigners making up only 25.1 percent, the 19th-lowest share among the city's neighborhoods. The population structure is balanced between generations: the old-age dependency ratio of 40.4 ranks third-highest, while the youth dependency ratio of 41.2 ranks second-highest, indicating that the area attracts both families and retirees.

Socially and economically, Bruderholz stands out as an affluent and stable community. The share of welfare recipients is just 1.2 percent, the lowest in Basel, and the unemployment rate of 2.4 percent is also among the lowest. The Gymnasium attendance rate of 54.6 percent is the highest in the city, reflecting a highly educated population. The share of long-term residents is 42.6 percent, suggesting a rooted and settled community. The average apartment size of 109.9 square meters and living space of 48.1 square meters per person are both among the highest in Basel, reinforcing the impression of spacious, comfortable living.